Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898583 | 1.00 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL253310 | 0.87 | MAPT (0.63) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL10526623 | 0.85 | CYP19A1 (0.46) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL9657076 | 0.84 | CYP19A1 (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL7454319 | 0.84 | CYP19A1 (0.48) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL30587346 | 0.84 | CYP19A1 (0.48) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL9656956 | 0.84 | CYP19A1 (0.45) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL9657046 | 0.83 | ALDH1A1 (0.52) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL10529139 | 0.83 | CYP19A1 (0.46) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL3156176 | 0.82 | MAPT (0.58) | MAPTKDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | claimed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| EP-1435228-A1 | Composition for dyeing keratin fibres comprising a triheteroylmethane direct dye or its leuco precursor and dyeing method | L'OREAL (FR) | 2004-07-07 | — | — | EP | claimed |
| US-12396938-B2 | Compositions and methods for coloring hair | L'OREAL (FR) | 2025-08-26 | — | — | US | disclosed |
| WO-2024050469-A1 | HAIR COLORING COMPOSITIONS | L'OREAL (FR) | 2024-03-07 | — | — | WO | disclosed |
| US-20240065956-A1 | COMPOSITIONS AND METHODS FOR COLORING HAIR | L'OREAL (FR) | 2024-02-29 | — | — | US | disclosed |
| US-11185485-B2 | Hair coloring compositions and methods of using the same | L'OREAL (FR) | 2021-11-30 | — | — | US | disclosed |
| US-20200375865-A1 | HAIR COLORING COMPOSITIONS AND METHODS OF USING THE SAME | L'OREAL (FR) | 2020-12-03 | — | — | US | disclosed |
| EP-2315615-B1 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR USING PERSULFATES, PERBORATES OR PERCARBONATES | OREAL (FR) | 2019-11-20 | — | — | EP | disclosed |
| EP-2916916-B1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | L'ORÉAL (FR) | 2018-01-10 | — | — | EP | disclosed |
| EP-2225003-B1 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR USING PERSULFATES, PERBORATES OR PERCARBONATES | L'ORÉAL (FR) | 2017-10-11 | — | — | EP | disclosed |
| US-7905926-B2 | Methods and kits for permanently coloring hair | L'ORÉAL (FR) | 2011-03-15 | — | — | US | disclosed |
| US-20100192969-A1 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR | L'OREAL (FR) | 2010-08-05 | — | — | US | disclosed |
| US-7611544-B2 | Methods of artificially coloring hair | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-7601179-B2 | Methods of preserving artificial coloring on keratin materials | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | disclosed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1435228-A1 | Composition for dyeing keratin fibres comprising a triheteroylmethane direct dye or its leuco precursor and dyeing method | L'OREAL (FR) | 2004-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375865-A1 | HAIR COLORING COMPOSITIONS AND METHODS OF USING THE SAME | PHOSPHO1, SGMS1, DEGS1 | MAPT 1516/4885KDM4E 2938/4885MEN1 2979/4885 |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | KRT18, KMO, KRTCAP2 | MAPT 174/4885KDM4E 936/4885MEN1 4090/4885 |
| US-11185485-B2 | Hair coloring compositions and methods of using the same | PHOSPHO1, SGMS1, DEGS1 | MAPT 1516/4885KDM4E 2938/4885MEN1 2979/4885 |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | HDAC10, RARA, PRDM7 | MAPT 2824/4885KDM4E 936/4885MEN1 2468/4885 |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | KRT18, CUTA, KDM6A | MAPT 696/4885KDM4E 69/4885MEN1 2612/4885 |
| US-20100192969-A1 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR | CYB5R3, COXFA4L2, PPOX | MAPT 4254/4885KDM4E 1928/4885MEN1 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.