SCHEMBL31567112

SCHEMBL31567112

CC(C)(C)[Si](C)(C)OCc1c[nH]nc1N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.33
▸ DUT P33316 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31283657 0.81 BACE1 (0.33) BACE1DUT
SCHEMBL15389825 0.71 BACE1 (0.42) BACE1DUT
SCHEMBL31284269 0.70 DUT (0.33) DUT
SCHEMBL3940682 0.70 BACE1 (0.44) BACE1
SCHEMBL5465604 0.70 BACE1 (0.39) BACE1
SCHEMBL14659892 0.70 AOC1 (0.37) BACE1
SCHEMBL4685077 0.70 BACE1 (0.37) BACE1DUT
SCHEMBL5743431 0.69 NOS2 (0.42) BACE1
SCHEMBL15539753 0.69 ATAD2 (0.38) —
SCHEMBL1010195 0.69 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473285-B2 DCN-1 modulating compounds and methods of use thereof CELLARITY, INC. (US) 2025-11-18 — — US disclosed
US-20250257063-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF THAMES PHARMA PARTNERS 2025-08-14 — — US disclosed
US-20250163057-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF THAMES PHARMA PARTNERS 2025-05-22 — — US disclosed
WO-2025096956-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF CELLARITY, INC. (US) 2025-05-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473285-B2 DCN-1 modulating compounds and methods of use thereof DCUN1D1, DCUN1D2, DCUN1D4 BACE1 4826/4885DUT 1255/4885
US-20250163057-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF DCUN1D1, DCUN1D2, DCUN1D4 BACE1 4826/4885DUT 1255/4885
US-20250257063-A1 DCN-1 MODULATING COMPOUNDS AND METHODS OF USE THEREOF DCUN1D1, DCUN1D2, DCUN1D4 BACE1 4826/4885DUT 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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