Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568122 | 0.81 | AR (0.40) | ALDH1A1ARMAPTHPGDCYP2C9 | |
| SCHEMBL31568121 | 0.79 | ALDH1A1 (0.42) | RAB9AALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8832774 | 0.77 | RAB9A (0.44) | RAB9ANPC1ALDH1A1LMNAKMT2A | |
| SCHEMBL8863220 | 0.76 | LMNA (0.46) | RAB9ANPC1ALDH1A1LMNAKMT2A | |
| SCHEMBL12932841 | 0.73 | PTGS2 (0.44) | MAPTL3MBTL1HTTCYP1A2CYP3A4 | |
| SCHEMBL9917309 | 0.71 | KMT2A (0.53) | ALDH1A1KMT2AMEN1TTRMAPT | |
| SCHEMBL10644798 | 0.71 | MAOA (0.43) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL12933383 | 0.70 | MTNR1A (0.50) | ALDH1A1CYP2C9CYP2C19CYP1A2CYP2E1 | |
| SCHEMBL13918976 | 0.69 | GRM5 (0.47) | MAPTL3MBTL1POLBMAPK1HTT | |
| SCHEMBL13220725 | 0.69 | KMT2A (0.50) | ALDH1A1KMT2AMEN1TTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894875-A | [4- [5- (Methylsulfonyl) -phenyl ] piperazin-1-yl ] - (phenyl) methanone derivatives and similar compounds having gfrα1-RET activity as neuroprotective agents for the treatment of neurological disorders | 基因密码公司 | 2025-04-25 | — | — | CN | disclosed |