Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757671 | 0.80 | CHRNB2 (0.53) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4812347 | 0.79 | CHRNB2 (0.51) | CHRNB2CHRNA4 | |
| SCHEMBL30961923 | 0.76 | POLB (0.46) | CHRNB2CHRNA4KCNH2 | |
| SCHEMBL5761331 | 0.75 | ALDH1A1 (0.47) | CHRNB2CHRNA4KCNH2 | |
| SCHEMBL5759446 | 0.72 | ALDH1A1 (0.47) | PIK3CAKDM4EMETAP2LRRK2 | |
| SCHEMBL1588164 | 0.72 | POLB (0.50) | KDM4EMETAP2 | |
| SCHEMBL7334933 | 0.71 | ADRB2 (0.58) | SYKPRKCHPRKCEKDM4ECCNT1 | |
| SCHEMBL30961905 | 0.71 | TIPARP (0.51) | KDM4E | |
| SCHEMBL15055212 | 0.69 | HTR3E (0.53) | PIK3CAOPRM1OPRL1 | |
| SCHEMBL17738687 | 0.68 | PIK3CA (0.43) | PRKCHPRKCEPIK3CAPIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113939295-B | Pyridazinones and methods of use thereof | 金翅雀生物公司 | 2025-05-16 | — | — | CN | disclosed |