Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748895 | 0.75 | SMN1; SMN2 (0.58) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL4868317 | 0.70 | HDAC6 (0.55) | ALDH1A1ADRA1AHDAC6SMN1; SMN2LMNA | |
| SCHEMBL8211578 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2CA1CA9 | |
| SCHEMBL11646152 | 0.69 | LMNA (0.40) | LMNA | |
| SCHEMBL31662452 | 0.69 | CA12 (0.42) | ALDH1A1HPGDLMNACA1CA9 | |
| SCHEMBL4289197 | 0.68 | CYP24A1 (0.46) | KDM4EHPGDSMN1; SMN2LMNACA1 | |
| SCHEMBL13327063 | 0.68 | PTGS2 (0.45) | ALDH1A1KDM4EHPGDCA1CA9 | |
| SCHEMBL14642669 | 0.68 | CDK1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10ADRA1A | |
| SCHEMBL27698392 | 0.68 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10ADRA1A | |
| SCHEMBL241884 | 0.67 | CA1 (0.52) | ALDH1A1HPGDSMN1; SMN2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636231-B1 | METHODS FOR PREPARING 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]-2-AMINOPURINE USING A COMPOUND OF 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES | KYUNGDONG PHARM CO LTD (KR) | 2010-03-24 | — | — | EP | disclosed |
| CN-100455583-C | 2-amino-9- (2-substituted ethyl) purines and methods of using same to prepare 9- [ 4-acetoxy-3- (acetoxymethyl) butan-1-yl ] -2-aminopurine | KYUNGDONG PHARM CO LTD (KR) | 2009-01-28 | — | — | CN | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-7456282-B2 | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2008-11-25 | — | — | US | disclosed |
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | KYUNGDONG PHARM. CO., LTD. (KR) | 2006-11-16 | — | — | US | disclosed |
| CN-1791602-A | 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9- 4-acetoxy-3-(acetoxymethyl)but-1-yl]- 2- aminopurine using the same | KYUNGDONG PHARM CO LTD (KR) | 2006-06-21 | — | — | CN | disclosed |
| EP-1636231-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9- 4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | Kyungdong Pharm. Co., Ltd. (KR) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110343-A2 | 2-AMINO-9-(2-SUBSTITUTED ETHYL)PURINES AND PREPARING METHODS FOR 9-[4-ACETOXY-3-(ACETOXYMETHYL)BUT-1-YL]- 2- AMINOPURINE USING THE SAME | KYUNGDONG PHARM. CO., LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258862-A1 | 2-Amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same | TYMP, TPMT, PNP | ALDH1A1 1015/4885KDM4E 783/4885HPGD 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.