Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281049 | 0.79 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL9037283 | 0.77 | CYP24A1 (0.53) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL3158247 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2HTTLMNAALDH1A1PKM | |
| SCHEMBL1581431 | 0.75 | PTGS2 (0.62) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL6609665 | 0.74 | HSD11B1 (0.47) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL8211578 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2HTTKMT2AALDH1A1POLB | |
| SCHEMBL1024585 | 0.73 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL352045 | 0.73 | SMN1; SMN2 (0.96) | SMN1; SMN2HTTMEN1KMT2ALMNA | |
| SCHEMBL31662452 | 0.73 | CA12 (0.42) | LMNAALDH1A1STAT3GAA | |
| SCHEMBL351186 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388587-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN SHANGHAI INC (CN) | 2025-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388587-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | ERBB2, MUSK, ERBB3 | SMN1; SMN2 607/4885HTT 1802/4885MEN1 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.