SCHEMBL31662452

SCHEMBL31662452

Cc1ccc(S(=O)(=O)OCCn2cnnc2)cc1.Cc1ccc(S(=O)(=O)OCCn2cnnc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
CYP2D6 P10635 2/20 0.40
ALDH1A1 P00352 5/20 0.39
PSMD10 O75832 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
VDR P11473 1/20 0.39
CYP24A1 Q07973 1/20 0.38
STAT3 P40763 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
CYP1A2 P05177 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979975 0.91 CYP24A1 (0.44) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL1464358 0.82 ALDH1A1 (0.57) CYP2D6ALDH1A1LMNACYP1A2
SCHEMBL241884 0.79 CA1 (0.52) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL3975042 0.79 L3MBTL1 (0.49) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL13327063 0.78 PTGS2 (0.45) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL11867519 0.77 PKM (0.41) CA12CA1CA9ALDH1A1PSMD10
SCHEMBL27602739 0.77 CA12 (0.46) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL11007032 0.77 PKM (0.50) CYP2D6ALDH1A1LMNAHPGDCYP1A2
SCHEMBL4592604 0.77 MMP2 (0.39) CA12CA1CA9CYP2D6ALDH1A1
SCHEMBL19733679 0.76 MBTD1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149545-A1 HETEROARYLPHENYL ETHER DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-07-17 WO disclosed