Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158392 | 1.00 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9653474 | 0.84 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9653470 | 0.84 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL578450 | 0.82 | ALOX15 (0.44) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6732281 | 0.81 | GLO1 (0.41) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6732284 | 0.81 | GLO1 (0.41) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL22572749 | 0.80 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL22912550 | 0.80 | ALOX15 (0.43) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28324138 | 0.79 | THRB (0.37) | ALOX15GLO1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1144348 | 0.76 | ALOX15 (0.52) | ALOX15GLO1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919732-A | Herbicidal 3-arylamino-6-trifluoromethyluracils | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-06 | — | — | US | claimed |
| US-8680290-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| EP-1789401-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2010-03-03 | — | — | EP | disclosed |
| US-20080139390-A1 | Isoxazoline Derivatives and Their Use as Herbicides | SYNGENTA LIMITED (GB) | 2008-06-12 | — | — | US | disclosed |
| EP-1789401-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024820-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |
| EP-0858997-B1 | Fungicides | SYNGENTA LTD (GB) | 2002-12-18 | — | — | EP | disclosed |
| EP-0808826-B1 | A method for preparing 3-amino substituted crotonates | ROHM & HAAS (US) | 2001-09-19 | — | — | EP | disclosed |
| US-6174839-B1 | AS HERBICIDE | NIHON BAYER AGROCHEM K.K. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-5935907-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0869123-A2 | Phenylacetylene derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0858997-A1 | Fungicides | ZENECA LIMITED (GB) | 1998-08-19 | — | — | EP | disclosed |
| US-5777154-A | Method for preparing 3-amino substituted crotonates | ROHM AND HAAS COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0808826-A1 | A method for preparing 3-amino substituted crotonates | ROHM AND HAAS COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| EP-0769495-A1 | Fungicides | ZENECA LIMITED (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5532208-A | HERBICIDES | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| WO-1995017096-A1 | HERBICIDAL HALOALKYLURACILS | FMC CORPORATION (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5399543-A | Chemical intermediates for the herbicides also claimed. | FMC CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5366955-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0568041-A1 | Pyrimidone derivatives and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139390-A1 | Isoxazoline Derivatives and Their Use as Herbicides | MTX1, MTX2, CHRM1 | ALOX15 3782/4885GLO1 1079/4885ALDH1A1 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.