SCHEMBL31589417

SCHEMBL31589417

NNC(=O)c1nccc(Cl)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 5/20 0.57
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
MPO P05164 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 5/20 0.37
MCL1 Q07820 1/20 0.37
KMO O15229 1/20 0.37
KDM5A P29375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282078 0.81 L3MBTL1 (0.38) P2RX7KDM4EL3MBTL1SMN1; SMN2GAA
SCHEMBL20837334 0.79 P2RX7 (0.59) P2RX7KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL1206986 0.79 MAP4K4 (0.40) ALDH1A1LMNASMN1; SMN2KMOPOLB
SCHEMBL31589613 0.78 ALDH1A1 (0.48) P2RX7KDM4EALDH1A1MAPTLMNA
SCHEMBL31589970 0.78 P2RX7 (0.57) P2RX7KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL25003139 0.77 KMO (0.68) P2RX7KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL2773643 0.76 KMO (0.41) ALDH1A1LMNASMN1; SMN2GAAKMO
SCHEMBL287227 0.76 KMO (0.58) KMO
SCHEMBL3120426 0.75 PRKCI (0.51) ALDH1A1MAPTLMNACYP1A2CYP3A4
SCHEMBL8159378 0.75 SORD (0.44) ALDH1A1SMN1; SMN2KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040437-A Novel heterocyclic compound and pharmaceutical composition comprising same 株式会社大熊制药 2025-05-27 CN disclosed