Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434974 | 0.77 | REN (0.40) | RENPKM | |
| SCHEMBL31637458 | 0.74 | PKM (0.38) | CFTRSIGMAR1RENPKM | |
| SCHEMBL31493475 | 0.74 | LRRK2 (0.39) | RENPKM | |
| SCHEMBL30522668 | 0.73 | THRB (0.45) | KDM4EHPGDALDH1A1 | |
| SCHEMBL8569059 | 0.73 | SIGMAR1 (0.58) | SIGMAR1RENHPGDHSP90AA1 | |
| SCHEMBL30639556 | 0.73 | POLB (0.43) | KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL27032969 | 0.73 | POLB (0.43) | KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL18865056 | 0.73 | THRB (0.45) | KDM4EHPGDALDH1A1 | |
| SCHEMBL31289933 | 0.71 | CA1 (0.55) | KDM4EL3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL31289996 | 0.71 | CA1 (0.55) | KDM4EL3MBTL1HPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171440-A1 | WRN INHIBITORS | NIMBUS WADJET, INC. | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171440-A1 | WRN INHIBITORS | WRN, BLM, RECQL | CFTR 611/4885SIGMAR1 4746/4885KDM4E 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.