Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31291699 | 0.77 | SLC6A4 (0.73) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31291661 | 0.77 | SLC6A4 (0.73) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31291638 | 0.77 | SIGMAR1 (0.53) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31622897 | 0.77 | KDM4E (0.41) | MAPTALDH1A1TRPA1TRPV1TP53 | |
| SCHEMBL31291768 | 0.77 | SIGMAR1 (0.53) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL31291712 | 0.76 | SLC6A4 (0.71) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL31291633 | 0.76 | SLC6A4 (0.71) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6353101 | 0.76 | TP53 (0.57) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6237350 | 0.75 | MAPKAPK2 (0.55) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8041738 | 0.74 | MAPKAPK2 (0.54) | SIGMAR1SLC6A4CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | ATAI THERAPEUTICS INC (US) | 2025-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197395-A1 | IBOGAINE AND NORIBOGAINE ANALOGS AND USES THEREOF | OPRM1, OPRK1, OPRD1 | SIGMAR1 7/4885SLC6A4 348/4885CHRNB2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.