Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414668 | 0.80 | DHFR (0.53) | ALDH1A1L3MBTL1DHFRMAPTPIN1 | |
| SCHEMBL9007010 | 0.77 | L3MBTL1 (0.39) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL2632674 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL1194395 | 0.77 | PIN1 (0.52) | DHFRPIN1 | |
| SCHEMBL2950586 | 0.77 | LMNA (0.42) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL14641049 | 0.74 | PIN1 (0.40) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL2625492 | 0.73 | L3MBTL1 (0.38) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL12590879 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CYP3A4L3MBTL1DHFRMAPT | |
| SCHEMBL18776173 | 0.73 | DAPK3 (0.44) | ALDH1A1L3MBTL1MAPTPIN1TDP1 | |
| SCHEMBL5789457 | 0.73 | HASPIN (0.44) | ALDH1A1L3MBTL1DHFRMAPTPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128873-A1 | HETEROCYCLIC PYRIDINONE COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025128848-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2025-06-19 | — | — | WO | disclosed |