Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205562 | 0.76 | CYP2A6 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL30286606 | 0.76 | CYP2A6 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL3163057 | 0.72 | HPRT1 (0.34) | — | |
| SCHEMBL14306804 | 0.71 | IMPDH2 (0.48) | MAOAMAOBIMPDH2IMPDH1NCOA3 | |
| SCHEMBL17297038 | 0.71 | IMPDH2 (0.48) | MAOAMAOBIMPDH2IMPDH1NCOA3 | |
| SCHEMBL3164250 | 0.69 | BACE1 (0.34) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4924946 | 0.68 | CYP2A6 (0.35) | MEN1KMT2A | |
| SCHEMBL11710597 | 0.68 | ALDH1A1 (0.41) | MAOAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11710324 | 0.68 | CDK2 (0.36) | ALDH1A1MEN1KMT2ADYRK1AAR | |
| SCHEMBL3165760 | 0.68 | NFE2L2 (0.37) | MAOAMAOBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334956-B1 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL CO (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-6916938-B2 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20030171589-A1 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-11 | — | — | US | disclosed |
| EP-1334956-A2 | Method for preparing sulfone or sulfoxide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171589-A1 | Method for preparing sulfone or sulfoxide compound | TST, SDHB, GPX4 | MAOA 1893/4885MAOB 208/4885IMPDH2 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.