Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649016 | 0.91 | HRH3 (0.36) | DPP4HRH3ALDH1A1HSD11B1 | |
| SCHEMBL31649339 | 0.89 | DPP4 (0.42) | DPP4HRH3FAPDPP8DPP9 | |
| SCHEMBL31649010 | 0.89 | HSD11B1 (0.38) | CCR1ALDH1A1HSD11B1UBE2MDCUN1D1 | |
| SCHEMBL31649243 | 0.87 | KMT2A (0.41) | DPP7ALDH1A1 | |
| SCHEMBL31649455 | 0.87 | KMT2A (0.41) | DPP7ALDH1A1 | |
| SCHEMBL31649051 | 0.86 | HTR2A (0.40) | ALDH1A1HTR2AOPRM1 | |
| SCHEMBL31649462 | 0.84 | ACHE (0.43) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL31649151 | 0.84 | ACHE (0.43) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL31649304 | 0.80 | NPC1 (0.39) | DPP4FAPDPP8DPP9HSD11B1 | |
| SCHEMBL31649284 | 0.78 | HSD11B1 (0.39) | DPP4DPP8ALDH1A1HSD11B1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |