Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649236 | 0.92 | DRD2 (0.47) | DRD2DRD4HSD11B1DPP4DPP7 | |
| SCHEMBL31649338 | 0.83 | DRD2 (0.43) | DRD2DRD4HSD11B1DPP4CCR1 | |
| SCHEMBL31649076 | 0.82 | DRD2 (0.43) | DRD2DRD4HSD11B1DPP4 | |
| SCHEMBL31649010 | 0.78 | HSD11B1 (0.38) | DRD2DRD4HSD11B1CCR1 | |
| SCHEMBL31649339 | 0.78 | DPP4 (0.42) | DRD2DRD4HSD11B1DPP4DPP7 | |
| SCHEMBL31649089 | 0.75 | DPP4 (0.41) | HSD11B1DPP4DPP7FAPDPP8 | |
| SCHEMBL31649406 | 0.75 | KMT2A (0.40) | DPP7 | |
| SCHEMBL31649053 | 0.75 | KMT2A (0.40) | DPP7 | |
| SCHEMBL31649221 | 0.75 | HSD11B1 (0.40) | DRD2DRD4HSD11B1 | |
| SCHEMBL31649260 | 0.75 | HTR2A (0.41) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |