Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649151 | 0.90 | ACHE (0.43) | HSD11B1UBE2MDCUN1D1 | |
| SCHEMBL31649462 | 0.90 | ACHE (0.43) | HSD11B1UBE2MDCUN1D1 | |
| SCHEMBL31649409 | 0.89 | RORC (0.40) | HSD11B1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31649065 | 0.87 | TACR1 (0.39) | HSD11B1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31649206 | 0.84 | OPRM1 (0.39) | HSD11B1KDM4E | |
| SCHEMBL31649010 | 0.83 | HSD11B1 (0.38) | HSD11B1MEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL31649185 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2ANPC1KDM4E | |
| SCHEMBL31649442 | 0.81 | PRSS1 (0.41) | HSD11B1MEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL31649269 | 0.79 | DPP4 (0.49) | HSD11B1SMN1; SMN2NPC1RAB9ACPT2 | |
| SCHEMBL31649413 | 0.79 | DPP4 (0.49) | HSD11B1SMN1; SMN2NPC1RAB9ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |