Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661357 | 0.88 | RET (0.36) | RETSOS1MEN1KMT2A | |
| SCHEMBL31661078 | 0.84 | CDK1 (0.32) | MEN1KMT2A | |
| SCHEMBL31661070 | 0.80 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL31661074 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL31661374 | 0.77 | CHKA (0.41) | — | |
| SCHEMBL31661359 | 0.74 | METAP2 (0.35) | METAP2 | |
| SCHEMBL31661330 | 0.74 | METAP2 (0.33) | METAP2 | |
| SCHEMBL31661323 | 0.72 | METAP2 (0.35) | METAP2 | |
| SCHEMBL31661341 | 0.72 | HTR6 (0.37) | METAP2 | |
| SCHEMBL31661349 | 0.70 | METAP2 (0.36) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |