Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661726 | 0.87 | USP1 (0.41) | S1PR1SMN1; SMN2HTTHDAC6HDAC8 | |
| SCHEMBL31661695 | 0.87 | S1PR1 (0.46) | S1PR1SMN1; SMN2TP53RXFP1NFKB1 | |
| SCHEMBL31661671 | 0.86 | S1PR1 (0.47) | S1PR1SMN1; SMN2KDM4E | |
| SCHEMBL31661611 | 0.83 | NPC1 (0.41) | NPC1RAB9AMEN1ALOX12KMT2A | |
| SCHEMBL31661802 | 0.81 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL31661724 | 0.80 | USP1 (0.41) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL31661744 | 0.79 | NR1H4 (0.50) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL31661762 | 0.79 | NR1H4 (0.50) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL31661790 | 0.77 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AS1PR1 | |
| SCHEMBL31661659 | 0.77 | LMNA (0.55) | NPC1RAB9AMEN1KMT2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |