Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376851 | 1.00 | CFTR (0.47) | CFTRMAPTL3MBTL1KDM4ENPC1 | |
| SCHEMBL1730308 | 0.82 | DHFR (0.48) | CFTRMAPTNPC1RAB9ALMNA | |
| SCHEMBL31661660 | 0.82 | MAPT (0.41) | MAPTL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL31661574 | 0.79 | POLB (0.47) | MAPTNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL31661507 | 0.78 | CYP1A2 (0.44) | MAPTL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL31661733 | 0.77 | RAB9A (0.45) | MAPTKDM4ERAB9ANPSR1PKM | |
| SCHEMBL18638439 | 0.76 | MAPT (0.50) | MAPTL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL8556009 | 0.75 | PKM (0.53) | MAPTL3MBTL1NPC1RAB9ALMNA | |
| SCHEMBL1014119 | 0.75 | KMT2A (0.56) | MAPTL3MBTL1CYP1A2KMT2AMEN1 | |
| SCHEMBL31661395 | 0.74 | CFTR (0.51) | CFTRMAPTL3MBTL1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151487-A2 | SMALL-MOLECULE INHIBITORS OF ADAR1 | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-07-17 | — | — | WO | disclosed |