Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730308 | 0.86 | DHFR (0.48) | RAB9ASMN1; SMN2MAPTCYP19A1MEN1 | |
| SCHEMBL31661574 | 0.85 | POLB (0.47) | MAPTALDH1A1CYP19A1KDM4CMEN1 | |
| SCHEMBL31661519 | 0.82 | MEN1 (0.46) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL1014119 | 0.81 | KMT2A (0.56) | MAPTMEN1KMT2A | |
| SCHEMBL31661440 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2MAPTKDM4EALDH1A1PKM | |
| SCHEMBL8626103 | 0.78 | MAPT (0.58) | SMN1; SMN2MAPTALDH1A1PKMKDM4C | |
| SCHEMBL31661685 | 0.77 | CFTR (0.47) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL3376851 | 0.77 | CFTR (0.47) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL8556009 | 0.77 | PKM (0.53) | RAB9ASMN1; SMN2MAPTPKMMEN1 | |
| SCHEMBL2643717 | 0.76 | PKM (0.65) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151487-A2 | SMALL-MOLECULE INHIBITORS OF ADAR1 | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-07-17 | — | — | WO | disclosed |