Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661802 | 0.93 | NPC1 (0.43) | NPC1HTTRAB9ALMNATHRB | |
| SCHEMBL31661744 | 0.85 | NR1H4 (0.50) | NPC1RAB9ALMNATHRBS1PR1 | |
| SCHEMBL31661762 | 0.85 | NR1H4 (0.50) | NPC1RAB9ALMNATHRBS1PR1 | |
| SCHEMBL31661724 | 0.83 | USP1 (0.41) | NPC1RAB9ATSHRS1PR1SMN1; SMN2 | |
| SCHEMBL31661659 | 0.83 | LMNA (0.55) | NPC1HTTRAB9ATSHRLMNA | |
| SCHEMBL31661726 | 0.79 | USP1 (0.41) | HTTS1PR1ALDH1A1SMN1; SMN2USP1 | |
| SCHEMBL31661695 | 0.79 | S1PR1 (0.46) | S1PR1SMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL31661671 | 0.78 | S1PR1 (0.47) | S1PR1SMN1; SMN2NPSR1USP1 | |
| SCHEMBL31661764 | 0.78 | RAB9A (0.43) | NPC1RAB9ALMNATHRBS1PR1 | |
| SCHEMBL22165856 | 0.77 | PTGS2 (0.44) | HTTTP53USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |