Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661808 | 0.81 | KRAS (0.45) | KRASKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL31661786 | 0.76 | ADRB2 (0.35) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31661745 | 0.76 | KRAS (0.35) | KRASGAASCN9AUSP1HTT | |
| SCHEMBL31661747 | 0.76 | KRAS (0.35) | KRASGAASCN9AUSP1HTT | |
| SCHEMBL31661812 | 0.72 | ADRB2 (0.45) | KDM4EALDH1A1HSD17B10USP1CYP3A4 | |
| SCHEMBL31661751 | 0.69 | KRAS (0.52) | KRASKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL24091680 | 0.66 | ALDH1A1 (0.86) | KRASKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL31661760 | 0.66 | USP1 (0.41) | KDM4EALDH1A1HSD17B10USP1CYP3A4 | |
| SCHEMBL31661763 | 0.66 | PTGS2 (0.39) | KDM4EALDH1A1HSD17B10USP1CYP3A4 | |
| SCHEMBL22122022 | 0.64 | ADORA2A (0.46) | KDM4EALDH1A1HSD17B10MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |