Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661812 | 0.88 | ADRB2 (0.45) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661807 | 0.81 | ADRB2 (0.41) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661730 | 0.81 | ADRB2 (0.41) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661796 | 0.81 | ADRB2 (0.43) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661786 | 0.79 | ADRB2 (0.35) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661763 | 0.78 | PTGS2 (0.39) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL22122022 | 0.76 | ADORA2A (0.46) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661804 | 0.76 | ADRB2 (0.42) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL31661785 | 0.73 | ALDH1A1 (0.44) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 | |
| SCHEMBL25255920 | 0.72 | USP1 (0.45) | USP1ALDH1A1KDM4ECYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |