Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662023 | 0.83 | PDK2 (0.42) | PDK2 | |
| SCHEMBL31662208 | 0.83 | HPGD (0.42) | NTRK1SCN9ADRD4SIGMAR1GPR119 | |
| SCHEMBL31661937 | 0.82 | PDE3B (0.39) | NTRK1SCN9ADRD4SIGMAR1ROCK2 | |
| SCHEMBL31662183 | 0.82 | SCN9A (0.39) | PDK2OPRM1NTRK1HTR3ASCN9A | |
| SCHEMBL31662441 | 0.81 | SCN9A (0.37) | NTRK1SCN9AROCK2PARP10 | |
| SCHEMBL31661868 | 0.81 | PDK2 (0.38) | PDK2NTRK1HTR3ASCN9ADRD4 | |
| SCHEMBL31662065 | 0.80 | PRKAB2 (0.39) | PDK2NTRK1HTR3ADRD4SIGMAR1 | |
| SCHEMBL31661880 | 0.79 | AXL (0.36) | NTRK1HTR3ASCN9AROCK2PARP10 | |
| SCHEMBL31662140 | 0.79 | GAA (0.46) | NTRK1DRD4SIGMAR1 | |
| SCHEMBL31662130 | 0.79 | PARP1 (0.40) | NTRK1SCN9AROCK2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |