Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662441 | 0.83 | SCN9A (0.37) | AXLPLK4NTRK1RETMET | |
| SCHEMBL31662023 | 0.81 | PDK2 (0.42) | SMN1; SMN2 | |
| SCHEMBL31662183 | 0.81 | SCN9A (0.39) | AXLPLK4NTRK1RETMET | |
| SCHEMBL31661868 | 0.81 | PDK2 (0.38) | AXLPLK4NTRK1RETMET | |
| SCHEMBL31662065 | 0.79 | PRKAB2 (0.39) | AXLPLK4NTRK1RETMET | |
| SCHEMBL31661852 | 0.79 | PDK2 (0.38) | NTRK1PARP10HTR3AROCK2SCN9A | |
| SCHEMBL31662208 | 0.79 | HPGD (0.42) | NTRK1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL31661937 | 0.78 | PDE3B (0.39) | NTRK1RAB9ASMN1; SMN2L3MBTL1ROCK2 | |
| SCHEMBL31662520 | 0.76 | AR (0.40) | AXLPLK4NTRK1RETMET | |
| SCHEMBL31662264 | 0.76 | SCN9A (0.40) | AXLPLK4NTRK1RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |