Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661984 | 0.86 | IKBKB (0.42) | MCHR2MCHR1PRMT5HRH3 | |
| SCHEMBL31662391 | 0.86 | GPR119 (0.37) | GPR119MCHR2MCHR1PDE1APDE1B | |
| SCHEMBL31662129 | 0.85 | MAPK1 (0.38) | GPR119PDE1APDE1BPDE1CSYK | |
| SCHEMBL31661918 | 0.82 | GPR119 (0.34) | GPR119PRMT5MAPK1 | |
| SCHEMBL31662113 | 0.77 | SCN9A (0.39) | SYKSCN9A | |
| SCHEMBL31662133 | 0.76 | OPRK1 (0.38) | SYKSCN9A | |
| SCHEMBL31662453 | 0.75 | MKNK1 (0.39) | SYKSCN9A | |
| SCHEMBL31662042 | 0.75 | IRAK4 (0.41) | SYKHRH3SCN9A | |
| SCHEMBL31662511 | 0.74 | SYK (0.38) | SYKSCN9A | |
| SCHEMBL31662493 | 0.73 | L3MBTL1 (0.41) | SYKSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |