Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661856 | 0.89 | GAA (0.35) | GAAPRMT5HPGDSMN1; SMN2 | |
| SCHEMBL31662349 | 0.82 | GPR119 (0.36) | GPR119PRMT5MAPK1 | |
| SCHEMBL31662129 | 0.79 | MAPK1 (0.38) | GPR119MAPK1 | |
| SCHEMBL31662391 | 0.78 | GPR119 (0.37) | GPR119PRMT5 | |
| SCHEMBL31661984 | 0.77 | IKBKB (0.42) | PRMT5 | |
| SCHEMBL31661966 | 0.76 | HPGD (0.39) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL31661959 | 0.75 | GAA (0.52) | GAAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL31662174 | 0.75 | TRPC6 (0.34) | GAAPRMT5 | |
| SCHEMBL31662124 | 0.74 | SCN9A (0.36) | — | |
| SCHEMBL31662493 | 0.71 | L3MBTL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |