Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662628 | 0.92 | KCNH2 (0.36) | KCNH2L3MBTL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL31662623 | 0.84 | MAPT (0.33) | KCNH2ALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL31662464 | 0.84 | MPO (0.41) | L3MBTL1ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL31662394 | 0.83 | CYP11B2 (0.35) | SMN1; SMN2MEN1KMT2ALMNACHRNB2 | |
| SCHEMBL31662398 | 0.80 | BMPR1B (0.34) | ALDH1A1NPC1HTTGCK | |
| SCHEMBL31662459 | 0.77 | TBXAS1 (0.40) | L3MBTL1ALDH1A1KMT2ACYP3A4CHEK2 | |
| SCHEMBL31662594 | 0.75 | MAPT (0.45) | L3MBTL1ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL31661943 | 0.73 | L3MBTL1 (0.35) | APPL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31662424 | 0.71 | PARP10 (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL31662366 | 0.69 | CA1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |