SCHEMBL31662464

SCHEMBL31662464

NNC(=O)c1cc(Oc2ccc(O)cc2)n2cncc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPO P05164 2/20 0.41
CYP3A4 P08684 2/20 0.41
BLM P54132 2/20 0.41
KDM5A P29375 1/20 0.41
GFER P55789 1/20 0.41
PMP22 Q01453 1/20 0.41
HIF1A Q16665 1/20 0.41
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP10 Q53GL7 1/20 0.35
ALDH1A1 P00352 7/20 0.35
KDM4E B2RXH2 6/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MAPT P10636 4/20 0.34
HTT P42858 3/20 0.34
GAA P10253 2/20 0.34
LMNA P02545 2/20 0.34
NSD2 O96028 1/20 0.34
ALPL P05186 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662424 0.86 PARP10 (0.48) MEN1KMT2APARP10ALDH1A1
SCHEMBL31662628 0.85 KCNH2 (0.36) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL31662366 0.84 CA1 (0.42) CYP3A4GFERALDH1A1KDM4ECA1
SCHEMBL31662272 0.84 KCNH2 (0.37) CYP3A4MEN1KMT2AALDH1A1HTT
SCHEMBL31662623 0.82 MAPT (0.33) MEN1KMT2AALDH1A1KDM4ECA1
SCHEMBL31662394 0.81 CYP11B2 (0.35) MEN1KMT2AGAALMNAPOLB
SCHEMBL31662223 0.80 KDM4E (0.41) CYP3A4MEN1KMT2AALDH1A1KDM4E
SCHEMBL31662398 0.78 BMPR1B (0.34) ALDH1A1KDM4EHTTNPC1
SCHEMBL31662459 0.74 TBXAS1 (0.40) CYP3A4BLMKMT2APARP10ALDH1A1
SCHEMBL31662321 0.73 ESR2 (0.39) CYP3A4KMT2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149545-A1 HETEROARYLPHENYL ETHER DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-07-17 WO disclosed