SCHEMBL31662775

SCHEMBL31662775

O=C1C(Cl)=C(Cl)C(O)N1Cc1ccc(N2CCNCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 7/20 0.45
HTR3E A5X5Y0 3/20 0.45
HTR3B O95264 3/20 0.45
HTR3A P46098 3/20 0.45
HTR3D Q70Z44 3/20 0.45
HTR3C Q8WXA8 3/20 0.45
SIGMAR1 Q99720 3/20 0.45
ALDH1A1 P00352 2/20 0.42
USP2 O75604 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CETP P11597 1/20 0.41
LTA4H P09960 2/20 0.40
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR6 P50406 2/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663172 0.85 RORC (0.39) ALDH1A1KDM4E
SCHEMBL31663179 0.83 TLR7 (0.39) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL31663164 0.83 ADRB1 (0.45) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL31662803 0.83 HTR1A (0.35) ADRB1ALDH1A1HTR6HTR1AHTR2A
SCHEMBL31663031 0.81 GFER (0.47) ALDH1A1TSHRHSD17B10THRBHTT
SCHEMBL31662701 0.80 HTR6 (0.37) HTR6TP53HTR1AHTR2AHTR2C
SCHEMBL31663040 0.80 ME2 (0.44) TP53HTR7LMNA
SCHEMBL31662779 0.79 KHK (0.43) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL24624436 0.76 CAPN1 (0.37) TP53KDM4ELMNA
SCHEMBL24624434 0.75 MAPT (0.42) ALDH1A1TP53HTTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed