SCHEMBL31663040

SCHEMBL31663040

NCC(=O)N1CCN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cc2)CC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ME2 P23368 2/20 0.44
ME1 P48163 2/20 0.44
ME3 Q16798 2/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GFER P55789 1/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 2/20 0.41
AKR1C3 P42330 1/20 0.41
MAPT P10636 3/20 0.40
GAA P10253 1/20 0.39
HTR7 P34969 1/20 0.39
TP53 P04637 1/20 0.39
ADAMTS5 Q9UNA0 1/20 0.39
GRM5 P41594 1/20 0.38
LMNA P02545 1/20 0.38
CACNA1G O43497 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663031 0.86 GFER (0.47) MEN1KMT2AGFERMAPTGAA
SCHEMBL31662883 0.81 GAA (0.38) ME2ME1ME3MEN1KMT2A
SCHEMBL31662801 0.81 SMN1; SMN2 (0.53) MEN1KMT2AMAPTTP53LMNA
SCHEMBL31662699 0.80 GAA (0.39) ME2ME1ME3MEN1KMT2A
SCHEMBL31662775 0.80 ADRB1 (0.45) HTR7TP53LMNA
SCHEMBL31662779 0.78 KHK (0.43) GAA
SCHEMBL31663172 0.74 RORC (0.39) KMT2APOLB
Hydrochloric Acid SCHEMBL6910714 0.73 AKR1C3 (0.66) ME2ME1ME3MEN1KMT2A
SCHEMBL31662790 0.73 LMNA (0.38) GFERMAPTTP53LMNA
SCHEMBL31662651 0.72 CA1 (0.40) MEN1KMT2AATMMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed