SCHEMBL31662832

SCHEMBL31662832

Cc1cc(N2CCNC(=O)C2)ccc1CN1C(=O)C(Cl)=C(Cl)C1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
WNT3A P56704 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
HSD11B1 P28845 1/20 0.33
DPP4 P27487 1/20 0.33
PDE7A Q13946 3/20 0.32
ADRB1 P08588 1/20 0.32
RORC P51449 1/20 0.32
IGF1R P08069 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
P2RX7 Q99572 2/20 0.31
OPRM1 P35372 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663164 0.88 ADRB1 (0.45) ADRB1P2RX7ALDH1A1
SCHEMBL31663172 0.84 RORC (0.39) WNT3AHSD11B1PDE7ARORCKMT2A
SCHEMBL31662798 0.76 KHK (0.42) ALDH1A1
SCHEMBL31662949 0.76 CCR1 (0.39) RORCMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL31662878 0.75 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2P2RX7ALDH1A1
SCHEMBL31662906 0.74 DPP4 (0.46) WNT3APDCD1CD274HSD11B1DPP4
SCHEMBL31662904 0.74 MAPT (0.35) RORCSMN1; SMN2ALDH1A1
SCHEMBL31662902 0.74 ALDH1A1 (0.35) HSD11B1ALDH1A1
SCHEMBL31662874 0.73 HPGDS (0.41) WNT3ASMN1; SMN2OPRM1ALDH1A1
SCHEMBL31662775 0.70 ADRB1 (0.45) ADRB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed