SCHEMBL31662874

SCHEMBL31662874

O=C1CN(c2ccc(CN3C(=O)C(Cl)=C(Cl)C3O)cn2)CCN1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.41
PIM1 P11309 3/20 0.35
PIM3 Q86V86 1/20 0.35
PIM2 Q9P1W9 1/20 0.35
ALDH1A1 P00352 1/20 0.34
PRMT5 O14744 1/20 0.34
CHRM1 P11229 1/20 0.33
EED O75530 1/20 0.33
SUZ12 Q15022 1/20 0.33
EZH2 Q15910 1/20 0.33
WNT3A P56704 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX5AP P20292 1/20 0.32
CCNT1 O60563 1/20 0.32
CDK4 P11802 1/20 0.32
CCND1 P24385 1/20 0.32
CCND3 P30281 1/20 0.32
CDK9 P50750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663179 0.87 TLR7 (0.39) HPGDSALDH1A1
SCHEMBL31663172 0.85 RORC (0.39) ALDH1A1WNT3AKDM4EHKDC1SMN1; SMN2
SCHEMBL31662802 0.81 RAB9A (0.41) KDM4E
SCHEMBL31662902 0.79 ALDH1A1 (0.35) ALDH1A1KDM4E
SCHEMBL31662784 0.78 GAA (0.43) ALDH1A1WNT3ACCNT1CDK9OPRM1
SCHEMBL31662817 0.74 GPR119 (0.50) WNT3ASMN1; SMN2RET
SCHEMBL31662886 0.74 HPGDS (0.45) HPGDSPIM1PIM3PIM2PRMT5
SCHEMBL26944604 0.74 HPGDS (0.45) HPGDSPIM1PIM3PIM2PRMT5
SCHEMBL31662775 0.73 ADRB1 (0.45) ALDH1A1CHRM1KDM4E
Hydrochloric Acid SCHEMBL26932372 0.73 HPGDS (0.44) HPGDSPIM1PIM3PIM2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025147756-A1 VIRAL SENSITIZERS COMPOSITIONS, METHODS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2025-07-17 WO disclosed