SCHEMBL31662969

SCHEMBL31662969

Cc1nc(OC[C@H](C)N)ccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 3/20 0.42
SCN5A Q14524 3/20 0.42
LMNA P02545 2/20 0.42
SCN1A P35498 2/20 0.42
SCN9A Q15858 2/20 0.42
HTR2A P28223 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
KCNK3 O14649 1/20 0.42
CACNA1F O60840 1/20 0.42
KCNK2 O95069 1/20 0.42
GBA1 P04062 1/20 0.42
MAOA P21397 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR2B P41595 1/20 0.42
SCN7A Q01118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153938 0.77 MAPT (0.37) LMNANFKB1
SCHEMBL2186001 0.75 SCN4A (0.47) SCN4ASCN5ALMNASCN1ASCN9A
SCHEMBL10811646 0.72 SCN4A (0.41) SCN4ASCN5ALMNASCN1ASCN9A
SCHEMBL14155360 0.72 SCN4A (0.41) SCN4ASCN5ALMNASCN1ASCN9A
SCHEMBL31663228 0.71 NR3C1 (0.33)
Hydrochloric Acid SCHEMBL10887122 0.71 LMNA (0.42) SCN4ASCN5ALMNASCN1ASCN9A
SCHEMBL13865700 0.70 NNMT (0.48) CYP1A2TSHR
SCHEMBL30142352 0.70 NNMT (0.48) CYP1A2TSHR
SCHEMBL8682006 0.67 PNMT (0.50) SCN4ALMNAKCNH2PNMTAKT1
SCHEMBL8682004 0.67 PNMT (0.50) SCN4ALMNAKCNH2PNMTAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149637-A1 NOVEL CARBOXAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-17 WO disclosed