Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161341 | 0.84 | KCNMA1 (0.50) | FAAHHCAR3GAAMGAMAMY1A | |
| SCHEMBL1161746 | 0.80 | FAAH (0.40) | FAAHHCAR3GAAF12KCNMA1 | |
| SCHEMBL31667519 | 0.80 | FAAH (0.40) | FAAHHCAR3GAAF12KCNMA1 | |
| SCHEMBL478164 | 0.68 | HCAR3 (0.50) | HCAR3HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL27601679 | 0.68 | HDAC3 (0.38) | HCAR3NPC1RAB9ANAMPT | |
| SCHEMBL18031574 | 0.67 | ALDH1A1 (0.44) | HCAR3GAAMGAMAMY1ASI | |
| SCHEMBL18031571 | 0.67 | KCNMA1 (0.54) | HCAR3GAAMGAMAMY1ASI | |
| SCHEMBL2222809 | 0.66 | P2RX4 (0.37) | HPGDP2RX4ALDH1A1NPC1RAB9A | |
| SCHEMBL3943731 | 0.66 | HDAC8 (0.42) | P2RX4ALDH1A1NPC1RAB9A | |
| SCHEMBL18033713 | 0.65 | HCAR3 (0.53) | HCAR3HPGDHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |