Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 1/20 | 0.69 |
| ▸ | TST | Q16762 | 1/20 | 0.69 |
| ▸ | VDR | P11473 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168280 | 1.00 | ALDH1A1 (0.69) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL10000887 | 1.00 | ALDH1A1 (0.69) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL13392549 | 1.00 | ALDH1A1 (0.69) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL9980567 | 1.00 | ALDH1A1 (0.69) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL14112630 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL14112640 | 0.93 | ALDH1A1 (0.58) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL6045249 | 0.90 | VDR (0.60) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL5438456 | 0.90 | VDR (0.60) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL5433038 | 0.90 | VDR (0.60) | ALDH1A1ALOX15CYP3A4LMNAADRA1A | |
| SCHEMBL10535348 | 0.89 | ALDH1A1 (0.53) | ALDH1A1ALOX15CYP3A4LMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093675-A1 | NOVEL METHOD | BIOXELL S.P.A. (IT) | 2010-04-15 | — | — | US | disclosed |
| US-20100069339-A1 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | BIOXELL S.P.A. (IT) | 2010-03-18 | — | — | US | disclosed |
| US-20100009949-A1 | NOVEL METHOD | BIOXELL S.P.A. (IT) | 2010-01-14 | — | — | US | disclosed |
| EP-2073814-A2 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | Bioxell S.p.a. (IT) | 2009-07-01 | — | — | EP | disclosed |
| EP-2063899-A2 | USE OF VITAMIN D COMPOUNDS FOR THE PREVENTION OF ADHESIONS | Bioxell S.p.a. (IT) | 2009-06-03 | — | — | EP | disclosed |
| US-20090137828-A1 | Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol | BIOXELL S.P.A. (IT) | 2009-05-28 | — | — | US | disclosed |
| WO-2008091686-A2 | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | BIOXELL S.P.A. (IT) | 2008-07-31 | — | — | WO | disclosed |
| EP-1924268-A2 | SYNTHESIS OF 1ALPHA-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | Bioxell S.p.a. (IT) | 2008-05-28 | — | — | EP | disclosed |
| WO-2008043857-A2 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | BIOXELL SPA (IT) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008034908-A2 | USE OF VITAMIN D COMPOUNDS FOR THE PREVENTION OF ADHESIONS | BIOXELL SPA (IT) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007110109-A1 | NOVEL METHOD | BIOXELL SPA (IT) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007022433-A2 | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | BIOXELL S.P.A. (IT) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069339-A1 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | CYP27B1, CYP2R1, SHBG | ALDH1A1 965/4885ALOX15 1984/4885CYP3A4 1018/4885 |
| US-20090137828-A1 | Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 137/4885ALOX15 56/4885CYP3A4 172/4885 |
| US-20100009949-A1 | NOVEL METHOD | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 1138/4885ALOX15 271/4885CYP3A4 1785/4885 |
| US-20100093675-A1 | NOVEL METHOD | GC, VDR, CYP24A1 | ALDH1A1 1409/4885ALOX15 146/4885CYP3A4 4138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.