SCHEMBL31685601

SCHEMBL31685601

Cn1c(=O)nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.61
▸ GMNN O75496 1/20 0.61
▸ ALDH1A1 P00352 1/20 0.61
▸ TP53 P04637 1/20 0.61
▸ NFKB1 P19838 1/20 0.61
▸ DNMT1 P26358 1/20 0.61
▸ THPO P40225 1/20 0.61
▸ MTOR P42345 1/20 0.61
▸ HTT P42858 1/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ BLM P54132 1/20 0.61
▸ HBB P68871 1/20 0.61
▸ PMP22 Q01453 1/20 0.61
▸ NT5E P21589 1/20 0.58
▸ HIF1A Q16665 1/20 0.58
▸ ADORA2A P29274 5/20 0.58
▸ ADORA2B P29275 3/20 0.58
▸ ADORA3 P0DMS8 3/20 0.58
▸ ADORA1 P30542 1/20 0.57
▸ DPP4 P27487 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685503 0.89 ADORA2A (0.51) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL31685661 0.86 ADORA1 (0.57) ADORA2AADORA2BADORA1
SCHEMBL31685537 0.86 CA5A (0.66) NT5EADORA1
SCHEMBL1979500 0.84 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL873210 0.84 LMNA (0.58) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL4778770 0.83 PAX8 (0.53) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL4778753 0.83 PAX8 (0.53) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL14614880 0.82 CYP2C19 (0.62) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL29762960 0.82 CYP2C19 (0.62) LMNAGMNNALDH1A1TP53NFKB1
SCHEMBL7152626 0.82 PAX8 (0.52) LMNAGMNNALDH1A1TP53NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 LMNA 240/4885GMNN 3368/4885ALDH1A1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback