Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.65 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28004326 | 0.86 | RXRA (0.55) | ADAMTS4DHODHDPP4DPP8 | |
| SCHEMBL11132637 | 0.82 | PTGS1 (0.70) | PTGS2AKR1C3AKR1C2MAPTPTGS1 | |
| SCHEMBL29941476 | 0.82 | DHODH (0.68) | ADAMTS4DHODHMAPTRECQLCYP3A4 | |
| SCHEMBL43553 | 0.80 | DHODH (0.70) | DHODHMAPTRECQLCYP3A4MAPK1 | |
| SCHEMBL7826539 | 0.80 | PTGS2 (1.00) | PTGS2AKR1C3AKR1C2MAPTPTGS1 | |
| SCHEMBL1211557 | 0.80 | PTGS2 (1.00) | PTGS2AKR1C3AKR1C2MAPTPTGS1 | |
| SCHEMBL29788172 | 0.80 | DHODH (0.70) | DHODHMAPTRECQLCYP3A4MAPK1 | |
| SCHEMBL6999225 | 0.80 | DHODH (0.63) | DHODHMAPTRECQLCYP3A4PMP22 | |
| Hydrochloric Acid SCHEMBL3973404 | 0.78 | DHODH (0.68) | DHODHMAPTRECQLCYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL5753890 | 0.78 | PTGS2 (0.96) | PTGS2AKR1C3AKR1C2MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | PTGS2 4529/4885ADAMTS4 3496/4885AKR1C3 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.