Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703486 | 0.80 | IDO1 (0.46) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL31703598 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL31703966 | 0.80 | IDO1 (0.46) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL31703383 | 0.80 | MTNR1B (0.50) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL7736294 | 0.70 | ALDH1A1 (0.78) | MEN1KMT2AGAAHTTNPC1 | |
| SCHEMBL31703747 | 0.70 | POLB (0.48) | MEN1KMT2AHTTNPSR1 | |
| SCHEMBL5346039 | 0.69 | HTT (0.60) | MEN1KMT2AHTTRECQLNPSR1 | |
| SCHEMBL16900136 | 0.66 | NPSR1 (0.67) | MEN1KMT2AHTTRECQLNPSR1 | |
| SCHEMBL3224693 | 0.66 | NPC1 (0.63) | MEN1KMT2AHTTRECQLNPSR1 | |
| SCHEMBL2558691 | 0.66 | NPSR1 (0.62) | MEN1KMT2AHTTRECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | claimed |
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |