Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703486 | 0.90 | IDO1 (0.46) | SMN1; SMN2ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL31703598 | 0.90 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL31703966 | 0.90 | IDO1 (0.46) | SMN1; SMN2ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL31703747 | 0.81 | POLB (0.48) | POLBMEN1KMT2A | |
| SCHEMBL31703579 | 0.80 | MEN1 (0.47) | SMN1; SMN2ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL31703740 | 0.76 | TACR2 (0.41) | — | |
| SCHEMBL31703416 | 0.76 | TACR2 (0.41) | — | |
| SCHEMBL31703485 | 0.75 | IDO1 (0.45) | SMN1; SMN2ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL31703444 | 0.72 | TACR2 (0.40) | — | |
| SCHEMBL11644190 | 0.70 | MTNR1B (0.78) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | claimed |
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |