Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703966 | 0.88 | IDO1 (0.46) | KMT2AMEN1FAAH | |
| SCHEMBL31703486 | 0.88 | IDO1 (0.46) | KMT2AMEN1FAAH | |
| SCHEMBL31703444 | 0.84 | TACR2 (0.40) | HRH3FAAH | |
| SCHEMBL31703416 | 0.81 | TACR2 (0.41) | HRH3FAAH | |
| SCHEMBL31703740 | 0.81 | TACR2 (0.41) | HRH3FAAH | |
| SCHEMBL31703383 | 0.81 | MTNR1B (0.50) | POLBKMT2AMEN1 | |
| SCHEMBL31703598 | 0.80 | ALDH1A1 (0.47) | KMT2AMEN1 | |
| SCHEMBL31703485 | 0.75 | IDO1 (0.45) | KMT2AMEN1 | |
| SCHEMBL31703420 | 0.72 | ALDH1A1 (0.56) | POLBKMT2AMEN1HTT | |
| SCHEMBL31703579 | 0.70 | MEN1 (0.47) | KMT2AMEN1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | claimed |
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |