SCHEMBL31713030

SCHEMBL31713030

O=C(Nc1ccc(CN2CCOCC2)cc1)c1ccccc1Cl

nearest known ligand 0.76

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 11/20 0.76
▸ NPC1 O15118 11/20 0.76
▸ SMN1; SMN2 Q16637 5/20 0.76
▸ TP53 P04637 3/20 0.76
▸ L3MBTL1 Q9Y468 1/20 0.71
▸ HIF1A Q16665 3/20 0.67
▸ EPAS1 Q99814 3/20 0.67
▸ KMT2A Q03164 2/20 0.63
▸ HTT P42858 1/20 0.62
▸ MAPK1 P28482 2/20 0.62
▸ MEN1 O00255 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18132519 0.88 RAB9A (0.76) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
SCHEMBL17740292 0.81 L3MBTL1 (0.72) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
SCHEMBL21657710 0.81 HIF1A (1.00) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
SCHEMBL11926732 0.80 ALDH1A1 (0.73) RAB9ANPC1SMN1; SMN2HIF1AEPAS1
SCHEMBL21024443 0.80 RAB9A (1.00) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
SCHEMBL28648364 0.80 RAB9A (1.00) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
Hydrochloric Acid SCHEMBL31072327 0.79 RAB9A (0.97) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
Hydrochloric Acid SCHEMBL31072328 0.79 RAB9A (0.97) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
Hydrochloric Acid SCHEMBL31072329 0.79 RAB9A (0.97) RAB9ANPC1SMN1; SMN2TP53L3MBTL1
SCHEMBL15932601 0.78 NPC1 (0.69) RAB9ANPC1SMN1; SMN2TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333387-A1 CRYSTALLINE CHLORO-N-(4-(MORPHOLINOMETHYL)PHENYL)BENZAMIDE AND CRYSTALLINE HYDROCHLORIDE SALT GEN1E LIFESCIENCES INC (US) 2025-10-30 — — US disclosed
WO-2025226445-A1 CRYSTALLINE CHLORO-N-(4-(MORPHOLINOMETHYL)PHENYL)BENZAMIDE AND CRYSTALLINE HYDROCHLORIDE SALT GEN1E LIFESCIENCES INC. (US) 2025-10-30 — — WO disclosed
WO-2025226445-A1 CRYSTALLINE CHLORO-N-(4-(MORPHOLINOMETHYL)PHENYL)BENZAMIDE AND CRYSTALLINE HYDROCHLORIDE SALT GEN1E LIFESCIENCES INC. (US) 2025-10-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333387-A1 CRYSTALLINE CHLORO-N-(4-(MORPHOLINOMETHYL)PHENYL)BENZAMIDE AND CRYSTALLINE HYDROCHLORIDE SALT UACA, MYOC, LPXN RAB9A 1438/4885NPC1 124/4885SMN1; SMN2 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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