SCHEMBL10068087

SCHEMBL10068087

CCCCOc1ccc2c(c1)C(=O)N([C@H](C(=O)O)C(C)(C)C)C2=O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
GAA P10253 1/20 0.49
RAB9A P51151 1/20 0.49
PTPN11 Q06124 3/20 0.42
PTPN1 P18031 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
MCL1 Q07820 1/20 0.39
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
PPARG P37231 1/20 0.39
CHRNA7 P36544 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315870 0.83 POLB (0.50) L3MBTL1KMT2AALDH1A1GAAPPARG
SCHEMBL10037556 0.80 L3MBTL1 (0.37) L3MBTL1KMT2AMAPTMEN1ALDH1A1
SCHEMBL316517 0.79 L3MBTL1 (0.38) L3MBTL1KMT2AMAPTMEN1ALDH1A1
SCHEMBL317136 0.76 MEN1 (0.53) KMT2AMEN1NPC1RAB9ATDP1
SCHEMBL2239457 0.74 PTPN11 (0.54) L3MBTL1KMT2AMAPTMEN1ALDH1A1
SCHEMBL8330397 0.74 LMNA (0.51) L3MBTL1ALDH1A1GAATDP1
SCHEMBL316573 0.74 LMNA (0.51) L3MBTL1ALDH1A1GAATDP1
SCHEMBL316754 0.73 POLB (0.47) L3MBTL1PPARG
SCHEMBL30353214 0.72 LMNA (0.50) L3MBTL1ALDH1A1GAATDP1
SCHEMBL11358368 0.68 MAPT (0.72) L3MBTL1KMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST PYM1, ARG1, SCO2 L3MBTL1 2735/4885KMT2A 305/4885MAPT 2790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.