Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476642 | 0.81 | DCTPP1 (0.52) | PDE1APDE1BPDE1CALDH1A1KDM4E | |
| SCHEMBL31714865 | 0.74 | CYP2C9 (0.36) | PDE1APDE1BPDE1CALDH1A1KDM4E | |
| SCHEMBL6900306 | 0.71 | MET (0.47) | ALDH1A1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL30020920 | 0.71 | MET (0.47) | ALDH1A1KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL20996061 | 0.67 | MAPT (0.41) | ALDH1A1KDM4EMAPTALOX15DCTPP1 | |
| SCHEMBL4101021 | 0.66 | NPBWR1 (0.50) | PDE1APDE1BPDE1CALDH1A1KDM4E | |
| SCHEMBL31715054 | 0.66 | APLNR (0.42) | ALDH1A1KDM4EDCTPP1SMN1; SMN2LMNA | |
| SCHEMBL25398080 | 0.63 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EALOX15SMN1; SMN2HTT | |
| SCHEMBL21883518 | 0.63 | MET (0.46) | ALDH1A1KDM4EMAPTALOX15L3MBTL1 | |
| SCHEMBL30021455 | 0.63 | MET (0.46) | ALDH1A1KDM4EMAPTALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2025-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250333424-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | PDE1A 4535/4885PDE1B 4613/4885PDE1C 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.