Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263225 | 0.85 | THRB (0.35) | ALDH1A1THRBTDP1ADORA3 | |
| SCHEMBL28754777 | 0.74 | ALDH1A1 (0.35) | ALDH1A1THRBALOX12TDP1APAF1 | |
| SCHEMBL28486941 | 0.74 | IDO1 (0.37) | ALDH1A1THRBALOX12TDP1APAF1 | |
| SCHEMBL5486167 | 0.72 | HTR5A (0.33) | TDP1L3MBTL1PDK2ADORA3 | |
| SCHEMBL5851114 | 0.71 | ADORA3 (0.35) | ALDH1A1THRBTDP1PDK2ADORA3 | |
| SCHEMBL24495475 | 0.70 | TDP1 (0.37) | ALDH1A1THRBTDP1POLBMAPT | |
| SCHEMBL27904709 | 0.70 | CHRM2 (0.39) | ALDH1A1TDP1MAPTADORA3MEN1 | |
| SCHEMBL28301722 | 0.69 | THRB (0.39) | ALDH1A1THRBTDP1L3MBTL1 | |
| SCHEMBL28438443 | 0.69 | NOTUM (0.31) | ALDH1A1NOTUM | |
| SCHEMBL14575103 | 0.68 | ADORA3 (0.33) | PDK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525456-B1 | METHOD AND APPARATUS FOR MEASURING WHITE BLOOD CELL COUNT | PORTASCIENCE INC (US) | 2010-03-31 | — | — | EP | disclosed |
| US-7323488-B2 | Chromogenic enzyme substrates | BURTON MICHAEL | 2008-01-29 | — | — | US | disclosed |
| EP-1525456-A4 | METHOD AND APPARATUS FOR MEASURING WHITE BLOOD CELL COUNT | PORTASCIENCE INC (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20060088941-A1 | Method and apparatus for measuring white blood cell count | PORTASCIENCE INC (US) | 2006-04-27 | — | — | US | disclosed |
| EP-1436411-B1 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2005-12-14 | — | — | EP | disclosed |
| US-20050124556-A1 | Chromogenic enzyme substrates | BURTON MICHAEL (GB) | 2005-06-09 | — | — | US | disclosed |
| EP-1525456-A1 | METHOD AND APPARATUS FOR MEASURING WHITE BLOOD CELL COUNT | Portascience Inc. (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1436411-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | Burton, Michael (GB) | 2004-07-14 | — | — | EP | disclosed |
| US-6709868-B2 | WASHING TO REMOVE RED BLOOD CELLS, READING COLOR REACTION OF ESTER PRESENT ON WHITE BLOOD CELLS CLEAVING CHROMOGENIC SUBSTRATE AND PRODUCING WATER INSOLUBLE DYE | PORTASCIENCE INC. | 2004-03-23 | — | — | US | disclosed |
| WO-2003100402-A1 | METHOD AND APPARATUS FOR MEASURING WHITE BLOOD CELL COUNT | PORTASCIENCE INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030215951-A1 | Method and apparatus for measuring white blood cell count | OXFORD FINANCE LLC, AS AGENT | 2003-11-20 | — | — | US | disclosed |
| WO-2003035896-A2 | CHROMOGENIC ENZYME SUBSTRATES AND METHOD FOR DETECTING BETA-D-RIBOFURANOSIDASE ACTIVITY | BURTON MICHAEL (GB) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124556-A1 | Chromogenic enzyme substrates | DCXR, MGAM, IDE | ALDH1A1 943/4885THRB 2075/4885ALOX12 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.