SCHEMBL19534945

SCHEMBL19534945

Cc1[c]c(C)c(-c2c(C)cc(C)cc2C)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.31
PDK2 Q15119 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3455954 0.83 MYC (0.37) PDK2CYP1A2CYP2A6
SCHEMBL4817133 0.78 MAPT (0.40) RAPGEF4CYP1A2CYP2A6
SCHEMBL9056633 0.76 CRHR1 (0.32) RAPGEF4
SCHEMBL11438609 0.75 MAOA (0.36) RAPGEF4CYP1A2CYP2A6
SCHEMBL317298 0.73 RAPGEF4 (0.33) RAPGEF4
SCHEMBL9509313 0.72 MAPT (0.45) RAPGEF4CYP1A2CYP2A6
SCHEMBL5795387 0.71 ACHE (0.36)
SCHEMBL2990872 0.71 HSD11B1 (0.33) CYP1A2CYP2A6
SCHEMBL15637267 0.71 ACHE (0.33)
SCHEMBL8734269 0.69 ACHE (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-07 US claimed