Kqikiwfqnkkmkwkk-Nh2

SCHEMBL31748869

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCCN)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	PTH1R	Q03431	8/20	0.60

▸	GHSR	Q92847	4/20	0.59

▸	KEAP1	Q14145	1/20	0.59

▸	IL23R	Q5VWK5	1/20	0.54

▸	TLR2	O60603	3/20	0.54

▸	RXFP1	Q9HBX9	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Penetratin SCHEMBL29356568	0.95	PTH1R (0.66)	PTH1RGHSRKEAP1IL23RRXFP1
Penetratin SCHEMBL29450548	0.93	KEAP1 (0.64)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL29710643	0.92	PTH1R (0.65)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL31749000	0.92	PTH1R (0.63)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL29350300	0.92	PTH1R (0.64)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL29429587	0.92	PTH1R (0.64)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL30299196	0.90	PTH1R (0.67)	PTH1RGHSRKEAP1IL23RRXFP1
SCHEMBL30617122	0.89	PTH1R (0.61)	PTH1RGHSRKEAP1IL23R
SCHEMBL31232534	0.88	PTH1R (0.68)	PTH1RKEAP1IL23RRXFP1
SCHEMBL30002139	0.88	PTH1R (0.63)	PTH1RKEAP1IL23RRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20250388619-A1	VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE	BIO SYNTHESIS INC (US)	2025-12-25	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20250388619-A1	VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE	RNMT, ADAR, RNGTT	PTH1R 1337/4885GHSR 2419/4885KEAP1 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.