Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404276 | 0.78 | — | — | |
| SCHEMBL6398895 | 0.73 | EPHX1 (0.45) | KMT2A | |
| SCHEMBL4364680 | 0.71 | ENPEP (0.37) | KMT2A | |
| SCHEMBL14930200 | 0.70 | ALDH1A1 (0.40) | — | |
| SCHEMBL3716659 | 0.69 | KMT2A (0.46) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL8722957 | 0.68 | CA2 (0.43) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL10837425 | 0.68 | CA2 (0.39) | CA1CA2 | |
| SCHEMBL6079159 | 0.68 | NOS3 (0.30) | — | |
| SCHEMBL1747943 | 0.67 | — | — | |
| SCHEMBL7770036 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | claimed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | claimed |