SCHEMBL4364680

SCHEMBL4364680

CC(=O)SC(CCS)CCCCC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 4/20 0.37
ALDH1A1 P00352 1/20 0.32
ANPEP P15144 1/20 0.32
GSTK1 Q9Y2Q3 2/20 0.31
MEN1 O00255 1/20 0.30
FAAH O00519 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30
SOAT1 P35610 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4362684 0.80 ENPEP (0.46) ENPEPALDH1A1ANPEPGSTK1CYP3A4
SCHEMBL3175406 0.71 ALOX15 (0.42) KMT2A
SCHEMBL13176808 0.70 ENPEP (0.31) ENPEP
SCHEMBL37411 0.70 ENPEP (0.39) ENPEPANPEPGSTK1MEN1FAAH
SCHEMBL27972090 0.70 GPR84 (0.42)
SCHEMBL26946027 0.69 PAOX (0.34) ENPEPALDH1A1GSTK1
SCHEMBL2576303 0.68 ENPEP (0.38) ENPEPANPEPGSTK1MEN1FAAH
SCHEMBL10307750 0.68 GSTK1 (0.48) ENPEPALDH1A1ANPEPGSTK1
SCHEMBL15135048 0.68 FOLH1 (0.44) ENPEPALDH1A1GSTK1
SCHEMBL3110906 0.68 ALDH1A1 (0.41) ENPEPALDH1A1GSTK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118714936-A Methods and uses of microbial compositions, components or metabolites for the treatment of vagal nerve related diseases, disorders and conditions 奇迹生物公司 2024-09-27 CN disclosed
CN-118265532-A Methods and uses of microbiome compositions, components or metabolites for treating neurodegenerative diseases 奇迹生物公司 2024-06-28 CN disclosed
US-20090186358-A1 Pathway Analysis of Cell Culture Phenotypes and Uses Thereof WYETH (US) 2009-07-23 US disclosed