Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | DDT | P30046 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808861 | 0.80 | RXRA (0.47) | RXRAGRIN1GRIN2BNOTUMESRRA | |
| SCHEMBL30808864 | 0.76 | ESRRA (0.44) | RXRAGRIN1GRIN2BNOTUMESRRA | |
| SCHEMBL30808857 | 0.76 | ESRRA (0.44) | NOTUMESRRAFAAHMGLL | |
| SCHEMBL28876225 | 0.76 | BTK (0.41) | RXRAGRIN1GRIN2BPARP1AR | |
| SCHEMBL30399860 | 0.76 | NOTUM (0.56) | NOTUMESRRAP2RY14CA1CA2 | |
| SCHEMBL19211469 | 0.76 | NOTUM (0.63) | RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL30808842 | 0.75 | MAOA (0.51) | NOTUMESRRACA1CA2CA4 | |
| SCHEMBL27137532 | 0.74 | RXRA (0.48) | RXRAGRIN1GRIN2BNOTUMAR | |
| SCHEMBL30399461 | 0.72 | NOTUM (0.57) | RXRAGRIN1GRIN2BNOTUMESRRA | |
| SCHEMBL30398809 | 0.71 | CA1 (0.59) | NOTUMESRRACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | ESCIENT PHARMACEUTICALS INC (US) | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001871-A1 | TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D | MRGPRX2, MC2R, MRGPRX1 | RXRA 527/4885GRIN1 412/4885GRIN2B 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.